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Hedgehog Pathway Agonism: Therapeutic Potential and Small-Molecule Development

by Hadden, M. Kyle
Published in ChemMedChem (2014)

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2

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Structure-Activity Relationship Studies of Vitamin D3 Analogues Containing an Ether or Thioether Linker as Hedgehog Pathway Inhibitors

by Wen, Jiachen, Hadden, M. Kyle
Published in ChemMedChem (2018)

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3

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Identification of Small Molecule Hes1 Modulators as Potential Anticancer Chemotherapeutics : Small Molecule Hes1 Modulators: Small Molecule Hes1 Modulators

by Sail, Vibhavari, Hadden, M. Kyle
Published in Chemical Biology & Drug Design (2013)

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4

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Introduction to Medicinal Chemistry: A Five-Day Course for High School Students

by Hadden, M. Kyle, Zaino, Angela M.
Published in Journal of Chemical Education (2020)

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5

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Targeting the Translesion Synthesis Pathway for the Development of Anti-Cancer Chemotherapeutics

by Korzhnev, Dmitry M., Hadden, M. Kyle
Published in Journal of Medicinal Chemistry (2016)

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6

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ChemInform Abstract: Oncoepigenomics: Making Histone Lysine Methylation Count

by DeCarlo, Daniel, Hadden, M. Kyle
Published in ChemInform (2013)

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7

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Synthesis and Evaluation of Radamide Analogues, A Chimera of Radicicol and Geldanamycin

by Hadden, M. Kyle, Blagg, Brian S. J.
Published in The Journal of Organic Chemistry (2009)

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8

Open Access

Probing the Protein-Protein Interaction between the ATRXADD Domain and the Histone H3 Tail

by Zaino, Angela M., Dash, Radha Charan, Hadden, M. Kyle
Published in Molecules (2020)

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9

Open Access

Truncated Itraconazole Analogues Exhibiting Potent Anti-Hedgehog Activity and Improved Drug-like Properties

by Wen, Jiachen, Chennamadhavuni, Divya, Morel, Shana R., Hadden, M. Kyle
Published in ACS Medicinal Chemistry Letters (2019)

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10

Open Access

Structure–Activity Relationships for Side Chain Oxysterol Agonists of Hedgehog Signaling

by Corman, Audrey, DeBerardinis, Albert M., Hadden, M. Kyle
Published in ACS Medicinal Chemistry Letters (2013)

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11

Open Access

Identification of Vitamin D3-Based Hedgehog Pathway Inhibitors That Incorporate an Aromatic A-Ring Isostere

by DeBerardinis, Albert M., Banerjee, Upasana, Hadden, M. Kyle
Published in ACS Medicinal Chemistry Letters (2013)

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12

Open Access

Structure–Activity Relationships for Side Chain Oxysterol Agonists of the Hedgehog Signaling Pathway

by Corman, Audrey, DeBerardinis, Albert M., Hadden, M. Kyle
Published in ACS Medicinal Chemistry Letters (2012)

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13

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Cellular uptake of a radiolabelled analogue of neurotensin in the Caco-2 cell model

by Hadden, M Kyle, Walle, Thomas, Dix, Thomas A
Published in Journal of Pharmacy and Pharmacology (2010)

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14

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Synthesis and Evaluation of Derrubone and Select Analogues

by Hastings, Jedidiah M., Hadden, M. Kyle, Blagg, Brian S. J.
Published in The Journal of Organic Chemistry (2008)

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15

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Asymmetric Synthesis of ω‐Bromo‐2(S)‐Methyl Acids as Precursors for Novel Arginine, Lysine, and Mercapto Residues

by Hadden, M. Kyle, Kokko, Kyle P., Dix, Thomas A.
Published in Synthetic Communications (2005)

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16

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Asymmetric Synthesis of ω-Bromo-2(S)-methyl Acids as Precursors for Novel Arginine, Lysine, and Mercapto Residues.

by Hadden, M. Kyle, Kokko, Kyle P., Dix, Thomas A.
Published in ChemInform (2005)

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17

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Formulation and evaluation of itraconazole liposomes for Hedgehog pathway inhibition

by Pace, Jennifer R., Jog, Rajan, Burgess, Diane J., Hadden, M. Kyle
Published in Journal of Liposome Research (2020)

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18

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Structural Approach To Identify a Lead Scaffold That Targets the Translesion Synthesis Polymerase Rev1

by Dash, Radha Charan, Ozen, Zuleyha, Rizzo, Alessandro A., Lim, Socheata, Korzhnev, Dmitry M., Hadden, M. Kyle
Published in Journal of Chemical Information and Modeling (2018)

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19

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Cover Picture: Synthesis and Evaluation of Osteogenic Oxysterols as Hedgehog Pathway Activators (ChemMedChem 7/2016)

by Maschinot, Chad A., Corman, Audrey R., DeBerardinis, Albert M., Hadden, M. Kyle
Published in ChemMedChem (2016)

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20

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Synthesis and Evaluation of Osteogenic Oxysterols as Hedgehog Pathway Activators

by Maschinot, Chad A., Corman, Audrey R., DeBerardinis, Albert M., Hadden, M. Kyle
Published in ChemMedChem (2016)

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