%0 Electronic Article %A Zhang, Rumeng and Zhu, Hongbo and Meng, Xin and Cao, Ziping and Chen, Guang and Tian, Laijin and Sun, Xuejun and You, Jinmao %I Wiley %D 2017 %D 2017 %G English %@ 1434-193X %@ 1099-0690 %~ Katalog UB TU-Chemnitz %T Base‐Mediated Domino Reaction of ortho‐Carbonylated Alkynyl‐Substituted Arenealdehydes with Indoles: Access to Indole‐Functionalized Isobenzofurans %V 2017 %J European Journal of Organic Chemistry %V 2017 %N 18 %P 2615-2620 %U http://dx.doi.org/10.1002/ejoc.201700050 %X A base‐mediated domino reaction of ortho‐carbonylated alkynyl‐substituted arenealdehydes with indoles has been developed, and a variety of indolyl‐substituted isobenzofuran derivatives can be rapidly obtained in high yields. Notably, the selective N‐alkylation of indoles and 5‐exodig cyclization of alkynes can be achieved efficiently to give N‐functionalized products. This reaction involves a domino procedure for the formation of two bonds under simple conditions and has a broad substrate scope. %Z https://katalog.bibliothek.tu-chemnitz.de/Record/ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9lam9jLjIwMTcwMDA1MA %U https://katalog.bibliothek.tu-chemnitz.de/Record/ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9lam9jLjIwMTcwMDA1MA