Eintrag weiter verarbeiten
Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs
Gespeichert in:
Zeitschriftentitel: | Journal of Biochemical and Molecular Toxicology |
---|---|
Personen und Körperschaften: | , , , , , , |
In: | Journal of Biochemical and Molecular Toxicology, 33, 2019, 7 |
Medientyp: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
Wiley
|
Schlagwörter: |
author_facet |
Zhao, Yuhang Su, Xin Gao, Yanrong Yin, Haijing Wang, Li Qiao, Rui Wang, Suhua Zhao, Yuhang Su, Xin Gao, Yanrong Yin, Haijing Wang, Li Qiao, Rui Wang, Suhua |
---|---|
author |
Zhao, Yuhang Su, Xin Gao, Yanrong Yin, Haijing Wang, Li Qiao, Rui Wang, Suhua |
spellingShingle |
Zhao, Yuhang Su, Xin Gao, Yanrong Yin, Haijing Wang, Li Qiao, Rui Wang, Suhua Journal of Biochemical and Molecular Toxicology Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs Health, Toxicology and Mutagenesis Toxicology Molecular Biology Molecular Medicine Biochemistry General Medicine |
author_sort |
zhao, yuhang |
spelling |
Zhao, Yuhang Su, Xin Gao, Yanrong Yin, Haijing Wang, Li Qiao, Rui Wang, Suhua 1095-6670 1099-0461 Wiley Health, Toxicology and Mutagenesis Toxicology Molecular Biology Molecular Medicine Biochemistry General Medicine http://dx.doi.org/10.1002/jbt.22334 <jats:title>Abstract</jats:title><jats:p>Chronic arsenic exposure through water intake is a worldwide issue, which has caused many diseases. Lungs are the first target organ of arsenic and lung inflammation, autophagy, and even the onset of tumors can be induced by arsenic exposure. Here, we tested the outcome of low‐concentration arsenic exposure in rat lungs. Tissue changes, inflammation, autophagy, and other physiological responses were observed in this study. Results showed that low‐concentration exposure of arsenite through water intake could initiate autophagy and inflammation in lungs but high concentration exposure produced a weak autophagy response and accentuated inflammation with the possibility of a chronic inflammation environment emerging followed by tumorigenesis.</jats:p> Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs Journal of Biochemical and Molecular Toxicology |
doi_str_mv |
10.1002/jbt.22334 |
facet_avail |
Online |
finc_class_facet |
Medizin Chemie und Pharmazie Biologie |
format |
ElectronicArticle |
fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9qYnQuMjIzMzQ |
id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9qYnQuMjIzMzQ |
institution |
DE-D275 DE-Bn3 DE-Brt1 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 DE-Ch1 DE-L229 |
imprint |
Wiley, 2019 |
imprint_str_mv |
Wiley, 2019 |
issn |
1095-6670 1099-0461 |
issn_str_mv |
1095-6670 1099-0461 |
language |
English |
mega_collection |
Wiley (CrossRef) |
match_str |
zhao2019exposureoflowconcentrationarsenicinitiatedinflammationandautophagyinratlungs |
publishDateSort |
2019 |
publisher |
Wiley |
recordtype |
ai |
record_format |
ai |
series |
Journal of Biochemical and Molecular Toxicology |
source_id |
49 |
title |
Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
title_unstemmed |
Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
title_full |
Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
title_fullStr |
Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
title_full_unstemmed |
Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
title_short |
Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
title_sort |
exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
topic |
Health, Toxicology and Mutagenesis Toxicology Molecular Biology Molecular Medicine Biochemistry General Medicine |
url |
http://dx.doi.org/10.1002/jbt.22334 |
publishDate |
2019 |
physical |
|
description |
<jats:title>Abstract</jats:title><jats:p>Chronic arsenic exposure through water intake is a worldwide issue, which has caused many diseases. Lungs are the first target organ of arsenic and lung inflammation, autophagy, and even the onset of tumors can be induced by arsenic exposure. Here, we tested the outcome of low‐concentration arsenic exposure in rat lungs. Tissue changes, inflammation, autophagy, and other physiological responses were observed in this study. Results showed that low‐concentration exposure of arsenite through water intake could initiate autophagy and inflammation in lungs but high concentration exposure produced a weak autophagy response and accentuated inflammation with the possibility of a chronic inflammation environment emerging followed by tumorigenesis.</jats:p> |
container_issue |
7 |
container_start_page |
0 |
container_title |
Journal of Biochemical and Molecular Toxicology |
container_volume |
33 |
format_de105 |
Article, E-Article |
format_de14 |
Article, E-Article |
format_de15 |
Article, E-Article |
format_de520 |
Article, E-Article |
format_de540 |
Article, E-Article |
format_dech1 |
Article, E-Article |
format_ded117 |
Article, E-Article |
format_degla1 |
E-Article |
format_del152 |
Buch |
format_del189 |
Article, E-Article |
format_dezi4 |
Article |
format_dezwi2 |
Article, E-Article |
format_finc |
Article, E-Article |
format_nrw |
Article, E-Article |
_version_ |
1792346687877939202 |
geogr_code |
not assigned |
last_indexed |
2024-03-01T17:43:07.763Z |
geogr_code_person |
not assigned |
openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Exposure+of+low%E2%80%90concentration+arsenic%E2%80%90initiated+inflammation+and+autophagy+in+rat+lungs&rft.date=2019-07-01&genre=article&issn=1099-0461&volume=33&issue=7&jtitle=Journal+of+Biochemical+and+Molecular+Toxicology&atitle=Exposure+of+low%E2%80%90concentration+arsenic%E2%80%90initiated+inflammation+and+autophagy+in+rat+lungs&aulast=Wang&aufirst=Suhua&rft_id=info%3Adoi%2F10.1002%2Fjbt.22334&rft.language%5B0%5D=eng |
SOLR | |
_version_ | 1792346687877939202 |
author | Zhao, Yuhang, Su, Xin, Gao, Yanrong, Yin, Haijing, Wang, Li, Qiao, Rui, Wang, Suhua |
author_facet | Zhao, Yuhang, Su, Xin, Gao, Yanrong, Yin, Haijing, Wang, Li, Qiao, Rui, Wang, Suhua, Zhao, Yuhang, Su, Xin, Gao, Yanrong, Yin, Haijing, Wang, Li, Qiao, Rui, Wang, Suhua |
author_sort | zhao, yuhang |
container_issue | 7 |
container_start_page | 0 |
container_title | Journal of Biochemical and Molecular Toxicology |
container_volume | 33 |
description | <jats:title>Abstract</jats:title><jats:p>Chronic arsenic exposure through water intake is a worldwide issue, which has caused many diseases. Lungs are the first target organ of arsenic and lung inflammation, autophagy, and even the onset of tumors can be induced by arsenic exposure. Here, we tested the outcome of low‐concentration arsenic exposure in rat lungs. Tissue changes, inflammation, autophagy, and other physiological responses were observed in this study. Results showed that low‐concentration exposure of arsenite through water intake could initiate autophagy and inflammation in lungs but high concentration exposure produced a weak autophagy response and accentuated inflammation with the possibility of a chronic inflammation environment emerging followed by tumorigenesis.</jats:p> |
doi_str_mv | 10.1002/jbt.22334 |
facet_avail | Online |
finc_class_facet | Medizin, Chemie und Pharmazie, Biologie |
format | ElectronicArticle |
format_de105 | Article, E-Article |
format_de14 | Article, E-Article |
format_de15 | Article, E-Article |
format_de520 | Article, E-Article |
format_de540 | Article, E-Article |
format_dech1 | Article, E-Article |
format_ded117 | Article, E-Article |
format_degla1 | E-Article |
format_del152 | Buch |
format_del189 | Article, E-Article |
format_dezi4 | Article |
format_dezwi2 | Article, E-Article |
format_finc | Article, E-Article |
format_nrw | Article, E-Article |
geogr_code | not assigned |
geogr_code_person | not assigned |
id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9qYnQuMjIzMzQ |
imprint | Wiley, 2019 |
imprint_str_mv | Wiley, 2019 |
institution | DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229 |
issn | 1095-6670, 1099-0461 |
issn_str_mv | 1095-6670, 1099-0461 |
language | English |
last_indexed | 2024-03-01T17:43:07.763Z |
match_str | zhao2019exposureoflowconcentrationarsenicinitiatedinflammationandautophagyinratlungs |
mega_collection | Wiley (CrossRef) |
physical | |
publishDate | 2019 |
publishDateSort | 2019 |
publisher | Wiley |
record_format | ai |
recordtype | ai |
series | Journal of Biochemical and Molecular Toxicology |
source_id | 49 |
spelling | Zhao, Yuhang Su, Xin Gao, Yanrong Yin, Haijing Wang, Li Qiao, Rui Wang, Suhua 1095-6670 1099-0461 Wiley Health, Toxicology and Mutagenesis Toxicology Molecular Biology Molecular Medicine Biochemistry General Medicine http://dx.doi.org/10.1002/jbt.22334 <jats:title>Abstract</jats:title><jats:p>Chronic arsenic exposure through water intake is a worldwide issue, which has caused many diseases. Lungs are the first target organ of arsenic and lung inflammation, autophagy, and even the onset of tumors can be induced by arsenic exposure. Here, we tested the outcome of low‐concentration arsenic exposure in rat lungs. Tissue changes, inflammation, autophagy, and other physiological responses were observed in this study. Results showed that low‐concentration exposure of arsenite through water intake could initiate autophagy and inflammation in lungs but high concentration exposure produced a weak autophagy response and accentuated inflammation with the possibility of a chronic inflammation environment emerging followed by tumorigenesis.</jats:p> Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs Journal of Biochemical and Molecular Toxicology |
spellingShingle | Zhao, Yuhang, Su, Xin, Gao, Yanrong, Yin, Haijing, Wang, Li, Qiao, Rui, Wang, Suhua, Journal of Biochemical and Molecular Toxicology, Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs, Health, Toxicology and Mutagenesis, Toxicology, Molecular Biology, Molecular Medicine, Biochemistry, General Medicine |
title | Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
title_full | Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
title_fullStr | Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
title_full_unstemmed | Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
title_short | Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
title_sort | exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
title_unstemmed | Exposure of low‐concentration arsenic‐initiated inflammation and autophagy in rat lungs |
topic | Health, Toxicology and Mutagenesis, Toxicology, Molecular Biology, Molecular Medicine, Biochemistry, General Medicine |
url | http://dx.doi.org/10.1002/jbt.22334 |