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![Buchumschlag von Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model](/Cover/Show?author=Fales%2C+Kevin+R.&callnumber=&size=medium&title=Discovery+of+N-%286-Fluoro-1-oxo-1%2C2-dihydroisoquinolin-7-yl%29-5-%5B%283R%29-3-hydroxypyrrolidin-1-yl%5Dthiophene-2-sulfonamide+%28LSN+3213128%29%2C+a+Potent+and+Selective+Nonclassical+Antifolate+Aminoimidazole-4-carboxamide+Ribonucleotide+Formyltransferase+%28AICARFT%29+Inhibitor+Effective+at+Tumor+Suppression+in+a+Can&recordid=ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAyMS9hY3Muam1lZGNoZW0uN2IwMTA0Ng&source=Solr&issn=0022-2623)
Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate A...
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| Zeitschriftentitel: | Journal of Medicinal Chemistry |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , , , , , , , , , , , , , , |
| In: | Journal of Medicinal Chemistry, 60, 2017, 23, S. 9599-9616 |
| Medientyp: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Chemical Society (ACS)
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| Schlagwörter: |