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HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China

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Zeitschriftentitel: Tissue Antigens
Personen und Körperschaften: Fu, Y., Liu, Z., Lin, J., Jia, Z., Chen, W., Pan, D., Liu, Y., Zhu, Y., Chen, R., Xu, A.
In: Tissue Antigens, 61, 2003, 2, S. 179-183
Medientyp: E-Article
Sprache: Englisch
veröffentlicht:
Wiley
Schlagwörter:
author_facet Fu, Y.
Liu, Z.
Lin, J.
Jia, Z.
Chen, W.
Pan, D.
Liu, Y.
Zhu, Y.
Chen, R.
Xu, A.
Fu, Y.
Liu, Z.
Lin, J.
Jia, Z.
Chen, W.
Pan, D.
Liu, Y.
Zhu, Y.
Chen, R.
Xu, A.
author Fu, Y.
Liu, Z.
Lin, J.
Jia, Z.
Chen, W.
Pan, D.
Liu, Y.
Zhu, Y.
Chen, R.
Xu, A.
spellingShingle Fu, Y.
Liu, Z.
Lin, J.
Jia, Z.
Chen, W.
Pan, D.
Liu, Y.
Zhu, Y.
Chen, R.
Xu, A.
Tissue Antigens
HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
Genetics
Biochemistry
Immunology
General Medicine
Immunology and Allergy
author_sort fu, y.
spelling Fu, Y. Liu, Z. Lin, J. Jia, Z. Chen, W. Pan, D. Liu, Y. Zhu, Y. Chen, R. Xu, A. 0001-2815 1399-0039 Wiley Genetics Biochemistry Immunology General Medicine Immunology and Allergy http://dx.doi.org/10.1034/j.1399-0039.2003.00012.x <jats:p><jats:bold>Abstract: </jats:bold> Polymorphism of HLA‐DRB1, DQB1 and DPB1 was revealed with a sequencing‐based typing (SBT) method in unrelated healthy volunteers from the Naxi ethnic group. Among the 43 DRB1 alleles detected, the most common allele was DRB1*12021 with a frequency of 17%, followed by DRB1*08032, DRB1*09012 and DRB1*1404 with frequencies of 8.5%, 7.4% and 7.4%, respectively. Among 23 DQB1 alleles detected, the most frequent DQB1 allele was DQB1*03011/0309 (21.9%), followed by DQB1*0502 (16.4%) and DQB1*05031 (9.6%). For the DPB1 locus, the most common alleles were DPB1*0501 (25.5%), DPB1*0402 (14.6%) and DPB1*02012 (12.0%). The most common DRB1‐DQB1‐DPB1 haplotype was DRB1*1404‐DQB1*05031‐DPB1*0402 with a frequency of 5.26%, followed by the DRB1*08032‐DQB1*06011‐DPB1*1301 (3.51%). The distribution characteristics of the HLA class II alleles revealed that the Naxi ethnic group belonged to the Southern group of Chinese.</jats:p> HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China Tissue Antigens
doi_str_mv 10.1034/j.1399-0039.2003.00012.x
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series Tissue Antigens
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title HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
title_unstemmed HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
title_full HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
title_fullStr HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
title_full_unstemmed HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
title_short HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
title_sort hla‐drb1, dqb1 and dpb1 polymorphism in the naxi ethnic group of south‐western china
topic Genetics
Biochemistry
Immunology
General Medicine
Immunology and Allergy
url http://dx.doi.org/10.1034/j.1399-0039.2003.00012.x
publishDate 2003
physical 179-183
description <jats:p><jats:bold>Abstract: </jats:bold> Polymorphism of HLA‐DRB1, DQB1 and DPB1 was revealed with a sequencing‐based typing (SBT) method in unrelated healthy volunteers from the Naxi ethnic group. Among the 43 DRB1 alleles detected, the most common allele was DRB1*12021 with a frequency of 17%, followed by DRB1*08032, DRB1*09012 and DRB1*1404 with frequencies of 8.5%, 7.4% and 7.4%, respectively. Among 23 DQB1 alleles detected, the most frequent DQB1 allele was DQB1*03011/0309 (21.9%), followed by DQB1*0502 (16.4%) and DQB1*05031 (9.6%). For the DPB1 locus, the most common alleles were DPB1*0501 (25.5%), DPB1*0402 (14.6%) and DPB1*02012 (12.0%). The most common DRB1‐DQB1‐DPB1 haplotype was DRB1*1404‐DQB1*05031‐DPB1*0402 with a frequency of 5.26%, followed by the DRB1*08032‐DQB1*06011‐DPB1*1301 (3.51%). The distribution characteristics of the HLA class II alleles revealed that the Naxi ethnic group belonged to the Southern group of Chinese.</jats:p>
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author Fu, Y., Liu, Z., Lin, J., Jia, Z., Chen, W., Pan, D., Liu, Y., Zhu, Y., Chen, R., Xu, A.
author_facet Fu, Y., Liu, Z., Lin, J., Jia, Z., Chen, W., Pan, D., Liu, Y., Zhu, Y., Chen, R., Xu, A., Fu, Y., Liu, Z., Lin, J., Jia, Z., Chen, W., Pan, D., Liu, Y., Zhu, Y., Chen, R., Xu, A.
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description <jats:p><jats:bold>Abstract: </jats:bold> Polymorphism of HLA‐DRB1, DQB1 and DPB1 was revealed with a sequencing‐based typing (SBT) method in unrelated healthy volunteers from the Naxi ethnic group. Among the 43 DRB1 alleles detected, the most common allele was DRB1*12021 with a frequency of 17%, followed by DRB1*08032, DRB1*09012 and DRB1*1404 with frequencies of 8.5%, 7.4% and 7.4%, respectively. Among 23 DQB1 alleles detected, the most frequent DQB1 allele was DQB1*03011/0309 (21.9%), followed by DQB1*0502 (16.4%) and DQB1*05031 (9.6%). For the DPB1 locus, the most common alleles were DPB1*0501 (25.5%), DPB1*0402 (14.6%) and DPB1*02012 (12.0%). The most common DRB1‐DQB1‐DPB1 haplotype was DRB1*1404‐DQB1*05031‐DPB1*0402 with a frequency of 5.26%, followed by the DRB1*08032‐DQB1*06011‐DPB1*1301 (3.51%). The distribution characteristics of the HLA class II alleles revealed that the Naxi ethnic group belonged to the Southern group of Chinese.</jats:p>
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spelling Fu, Y. Liu, Z. Lin, J. Jia, Z. Chen, W. Pan, D. Liu, Y. Zhu, Y. Chen, R. Xu, A. 0001-2815 1399-0039 Wiley Genetics Biochemistry Immunology General Medicine Immunology and Allergy http://dx.doi.org/10.1034/j.1399-0039.2003.00012.x <jats:p><jats:bold>Abstract: </jats:bold> Polymorphism of HLA‐DRB1, DQB1 and DPB1 was revealed with a sequencing‐based typing (SBT) method in unrelated healthy volunteers from the Naxi ethnic group. Among the 43 DRB1 alleles detected, the most common allele was DRB1*12021 with a frequency of 17%, followed by DRB1*08032, DRB1*09012 and DRB1*1404 with frequencies of 8.5%, 7.4% and 7.4%, respectively. Among 23 DQB1 alleles detected, the most frequent DQB1 allele was DQB1*03011/0309 (21.9%), followed by DQB1*0502 (16.4%) and DQB1*05031 (9.6%). For the DPB1 locus, the most common alleles were DPB1*0501 (25.5%), DPB1*0402 (14.6%) and DPB1*02012 (12.0%). The most common DRB1‐DQB1‐DPB1 haplotype was DRB1*1404‐DQB1*05031‐DPB1*0402 with a frequency of 5.26%, followed by the DRB1*08032‐DQB1*06011‐DPB1*1301 (3.51%). The distribution characteristics of the HLA class II alleles revealed that the Naxi ethnic group belonged to the Southern group of Chinese.</jats:p> HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China Tissue Antigens
spellingShingle Fu, Y., Liu, Z., Lin, J., Jia, Z., Chen, W., Pan, D., Liu, Y., Zhu, Y., Chen, R., Xu, A., Tissue Antigens, HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China, Genetics, Biochemistry, Immunology, General Medicine, Immunology and Allergy
title HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
title_full HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
title_fullStr HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
title_full_unstemmed HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
title_short HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
title_sort hla‐drb1, dqb1 and dpb1 polymorphism in the naxi ethnic group of south‐western china
title_unstemmed HLA‐DRB1, DQB1 and DPB1 polymorphism in the Naxi ethnic group of South‐western China
topic Genetics, Biochemistry, Immunology, General Medicine, Immunology and Allergy
url http://dx.doi.org/10.1034/j.1399-0039.2003.00012.x