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Buchumschlag von Research on Hemocompatibility of Polypropylene Non-Woven Fabric Membrane Immobilized by N-Alkylglucosamides
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Research on Hemocompatibility of Polypropylene Non-Woven Fabric Membrane Immobilized by N-Alkylglucosamides

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Zeitschriftentitel: Advanced Materials Research
Personen und Körperschaften: Xin, Zhi Rong, Yang, Zong Feng, Yan, Shun Jie, Du, Bin Bin
In: Advanced Materials Research, 704, 2013, S. 301-306
Medientyp: E-Article
Sprache: Unbestimmt
veröffentlicht:
Trans Tech Publications, Ltd.
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Zusammenfassung: <jats:p>New types of ecologically benign surfactants with sugar as head groups (N-alkylglucosamides) have been described, namely, N-octylglucosamides (NOGA), N-dodecylglucosamides (NDGA), N-cetylglucosamides (NCGA). N-alkylglucosamides were characterized by Fourier transform infrared spectroscopy (FTIR) and<jats:sup>1</jats:sup>H Nuclear Magnetic Resonance (<jats:sup>1</jats:sup>HNMR) respectively. N-alkylglucosamides was immobilized onto the surface of PPNWF by using Glycidyl methacrylate (GMA) as the linking agent. The chemical structure and composition of the modified PPNWF surface were analyzed by attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and X-ray photoelectron spectroscopy (XPS). The surface properties were investigated by water contact angle. The water contact angles of the modified PPNWF decreased from 111° to 73°. The hemocompatibility of the modified PPNWF was evaluated by platelet adhesion. The number of platelets adhering to the modified surface was more dramatically reduced than that of the virgin surface. The results indicate that the modified surface of PPNWF by N-alkylglucosamides was a facile approach to construct biocompatible surface.</jats:p>
Umfang: 301-306
ISSN: 1662-8985
DOI: 10.4028/www.scientific.net/amr.704.301